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Promethazine is used for treatment of allergies to the upper respiratory tract and skin including symptoms of sneezing, runny and itchy nose and eye irritation and red, raised, itchy skin rash. It is also used to prevent and control nausea, vomiting and pain which may occur after surgery; to prevent motion sickness. It also used as a short-term sedative.

It acts by blocking a natural substance called histamine that your body produces during an allergic reaction.

• Do not drive or operate machinery after taking promethazine if you feel drowsy.
• Do not use promethazine for more than 7 days without doctor’s advice.
• Do not use in patients in coma or suffering from depression.
• Doctor’s advice should be considered in case of following disease conditions: severe coronary artery disease, narrow angle glaucoma, epilepsy (fits) or liver or kidney problem, block in the junction of stomach and intestine (pyloro-duodenal obstruction) or in the bladder neck.

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